You may have read last week about the zero-day Adobe vulnerability. Sera-Brynn identified this morning that this specific vulnerability is being actively exploited in the wild via underground exploit kits.
Sera-Brynn recommends that Flash be temporarily disabled in all browsers until Adobe puts a successful patch in place.
Find more information on the exploit in the link below. The link is safe despite the name “malware” in the title. This link also provides cutting edge indicators of compromise that you may be able to ingest to existing sensors.
UPDATE 27Jan15: Adobe has released the new patch: http://thehackernews.com/2015/01/adobe-flash-player-update.html